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Product Name Anti-METTL21D/AF594 Chinese Name AF594标记的甲基化样蛋白21D抗体 Alias C14orf138; Methyltransferase like 21D; Methyltransferase-like protein 21D; Mettl21d; MT21D_HUMAN; Protein lysine methyltransferase METTL21D; Valosin containing protein lysine (K) methyltransferase; Valosin containing protein lysine methyltransferase; VCP KMT; VCP lysine methyltransferase; VCPKMT. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 25kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human METTL21D Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity.
Subunit:
Interacts with ALKBH6. Interacts with ASPSCR1 and UBXN6; interaction with ASPSCR1, but not with UBXN6, enhances VCP methylation.
Subcellular Location:
Cytoplasm
Similarity:
Belongs to the methyltransferase superfamily. METTL21 family.
Database links:Entrez Gene: 79609 Human
Entrez Gene: 207965 Mouse
Omim: 615260 Human
SwissProt: Q9H867 Human
SwissProt: Q8C436 Mouse
Unigene: 558541 Human
Unigene: 102487 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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