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Product Name Anti-Nkx6.3/AF594 Chinese Name AF594标记的转录因子同源蛋白Nkx6.3抗体 Alias FLJ25169; Homeobox protein Nkx 6.3; Homeobox protein Nkx-6.3; NK6 homeobox 3; NKX6-3; NKX6.3; NKX63; NKX63_HUMAN. Research Area Cell biology Developmental biology transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 28kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Nkx6.3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The NKX family of homeodomain proteins controls numerous developmental processes. Members of the NKX6 subfamily, including NKX6-3, are involved in development of the central nervous system (CNS), gastrointestinal tract, and pancreas (Alanentalo et al., 2006 [PubMed 16326147]).[supplied by OMIM, Mar 2008]
Function:
Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 homeobox DNA-binding domain.
Database links:Entrez Gene: 157848 Human
Entrez Gene: 74561 Mouse
Omim: 610772 Human
SwissProt: A6NJ46 Human
SwissProt: Q3UHX8 Mouse
Unigene: 647132 Human
Unigene: 290028 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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