Product Name	Anti-MMP21/AF555
Chinese Name	AF555标记的基质金属蛋白酶21抗体
Alias	Matrix metalloproteinase 21; MIFR; MMP21_HUMAN; MMP 21.
Research Area	Tumour  Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Horse, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	49kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MMP21
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and tumor metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. [provided by RefSeq, May 2013] Function: May have an important and specific function in tumor progression and embryogenesis. Cleaves alpha-1-antitrypsin. Subcellular Location: Secreted Tissue Specificity: Identified in fetal brain, kidney and liver. In adult tissues found primarily in ovary, kidney, liver, lung, placenta, brain and peripheral blood leukocytes. Expressed as well in various cancer cell lines. Post-translational modifications: The precursor is cleaved by a furin endopeptidase Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin repeats. Database links: Entrez Gene: 118856 Human Entrez Gene: 214766 Mouse Entrez Gene: 293573 Rat Omim: 608416 Human SwissProt: Q8N119 Human SwissProt: Q8K3F2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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