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Product Name Anti-ZDHHC23/AF555 Chinese Name AF555标记的ZDHHC23蛋白抗体 Alias DHHC-23; DHHC-containing protein 11; Gm1751; Gm779; nidd; Probable palmitoyltransferase ZDHHC23; ZDH23_HUMAN; Zdhhc23; Zinc finger DHHC domain-containing protein 23. Research Area Cell biology immunology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 46kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZDHHC23 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
ZDHHC23 is a 409 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. ZDHHC23 may play a role in NOS1 regulation and targets the synaptic membrane. By regulating the enzymatic activity of NOS1, ZDHHC23 may effect different pathological conditions including nerve regeneration, neuron loss or survival and pain processing.
Function:
May be involved in NOS1 regulation and targeting to the synaptic membrane.
Subcellular Location:
Membrane.
Similarity:
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger.
Database links:Entrez Gene: 254887 Human
Entrez Gene: 332175 Mouse
SwissProt: Q8IYP9 Human
SwissProt: Q5Y5T3 Mouse
Unigene: 21902 Human
Unigene: 327852 Mouse
Unigene: 43304 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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