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Rabbit Anti-ZDHHC23/AF555 Conjugated antibody
Rabbit Anti-ZDHHC23/AF555 Conjugated antibody
DHHC-23; DHHC-containing protein 11; Gm1751; Gm779; nidd; Probable palmitoyltransferase ZDHHC23; ZDH23_HUMAN; Zdhhc23; Zinc finger DHHC domain-containing protein 23.
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  • NO.:SL18482R-AF555
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Details

Product Name Anti-ZDHHC23/AF555
Chinese Name AF555标记的ZDHHC23蛋白抗体
Alias DHHC-23; DHHC-containing protein 11; Gm1751; Gm779; nidd; Probable palmitoyltransferase ZDHHC23; ZDH23_HUMAN; Zdhhc23; Zinc finger DHHC domain-containing protein 23.  
Research Area Cell biology  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 46kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZDHHC23
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
ZDHHC23 is a 409 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. ZDHHC23 may play a role in NOS1 regulation and targets the synaptic membrane. By regulating the enzymatic activity of NOS1, ZDHHC23 may effect different pathological conditions including nerve regeneration, neuron loss or survival and pain processing.

Function:
May be involved in NOS1 regulation and targeting to the synaptic membrane.

Subcellular Location:
Membrane.

Similarity:
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger.

Database links:

Entrez Gene: 254887 Human

Entrez Gene: 332175 Mouse

Entrez Gene: 363783 Rat

SwissProt: Q8IYP9 Human

SwissProt: Q5Y5T3 Mouse

SwissProt: Q76IC6 Rat

Unigene: 21902 Human

Unigene: 327852 Mouse

Unigene: 43304 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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