Product Name	Anti-SPANXD/CT11.4/AF555
Chinese Name	AF555标记的癌/睾丸抗原11.4抗体
Alias	Cancer/testis antigen 11.4; Cancer/testis antigen family 11 member 4; CT11.4; dJ171K16.1; Nuclear associated protein SPAN Xd; Nuclear-associated protein SPAN-Xd; SPAN Xd protein; SPANX C; SPANX D; SPANX family member D; SPANX-D; SPANXD; Sperm protein associated with the nucleus on the X chromosome D; Sperm protein associated with the nucleus X chromosome family member D; SPNXD_HUMAN.
Research Area	Tumour  Cell biology  Developmental biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	11kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPANXD/CT11.4
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014] Subcellular Location: Cytoplasm. Nucleus. Associated with nuclear craters. Tissue Specificity: Detected in testis, sperm and a melanoma cell line. Similarity: Belongs to the SPAN-X family. Database links: Entrez Gene: 64648 Human Omim: 300670 Human SwissProt: Q9BXN6 Human Unigene: 375036 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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