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Product Name Anti-NME6/AF488 Chinese Name AF488标记的P53诱导Apoptosis抑制蛋白α抗体 Alias Inhibitor of p53 induced apoptosis alpha; Inhibitor of p53-induced apoptosis-alpha; IPIA ALPHA; IPIA-alpha; NDK 6; NDK6_HUMAN; NDP kinase 6; NM23 H6; nm23-H6; NM23H6; Nme6. Research Area Tumour Cell biology Signal transduction Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 21kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NME6/IPIA ALPHA Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Tissue specificity: Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.
Function:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Tissue Specificity:
Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.
Similarity:
Belongs to the NDK family.
Database links:Entrez Gene: 10201 Human
Entrez Gene: 54369 Mouse
Omim: 608294 Human
SwissProt: O75414 Human
SwissProt: O88425 Mouse
Unigene: 465558 Human
Unigene: 12951 Mouse
Unigene: 36170 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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