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Product Name Anti-ZNF185/AF350 Chinese Name AF350标记的Zinc finger protein185抗体 Alias LIM domain protein ZNF185; P1 A; P1-A; Zinc finger protein 185 (LIM domain); Zinc finger protein 185; ZN185_HUMAN; ZNF185. Research Area Tumour Cell biology Zinc finger protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 74kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNF185 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
Function:
May be involved in the regulation of cellular proliferation and/or differentiation.
Subcellular Location:
Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
Tissue Specificity:
Expressed in placenta, pancreas and kidney. Also expressed in prostate, testis, ovary and blood.
Similarity:
Contains 1 LIM zinc-binding domain.
Database links:
Entrez Gene: 7739 Human
Entrez Gene: 22673 Mouse
Omim: 300381 Human
SwissProt: O15231 Human
SwissProt: Q62394 Mouse
Unigene: 16622 Human
Unigene: 1161 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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