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Product Name Anti-MS4A12/AF350 Chinese Name AF350标记的MS4A12蛋白抗体 Alias FLJ20217; Membrane spanning 4 domains subfamily A member 12. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 28kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MS4A12 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Function:
MS4A12 (Membrane-spanning 4-domains, subfamily A, member 12) is a member of the membrane-spanning 4A gene family which share structural similarity, amino acid sequence homology, and chromosomal location. It may be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the MS4A family.
Database links:Entrez Gene: 54860 Human
Omim: 606550 Human
SwissProt: Q9NXJ0 Human
Unigene: 272789 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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