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Rabbit Anti-ACOX2/AF350 Conjugated antibody
Rabbit Anti-ACOX2/AF350 Conjugated antibody
ACOX 2; Acyl Coenzyme A oxidase 2; Acyl Coenzyme A oxidase 2 branched chain; Acyl coenzyme A oxidase 2 peroxisomal; BCOX; BRCACOX; BRCOX; Peroxisomal branched chain acyl CoA oxidase; THCA CoA oxidase; THCCox; Trihydroxycoprostanoyl CoA oxidase; 3 alpha 7
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  • NO.:SL5030R-AF350
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,Rat,(predicted: Human,Cow,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-ACOX2/AF350
Chinese Name AF350标记的过氧化物酶酰基辅酶A氧化酶2抗体
Alias ACOX 2; Acyl Coenzyme A oxidase 2; Acyl Coenzyme A oxidase 2 branched chain; Acyl coenzyme A oxidase 2 peroxisomal; BCOX; BRCACOX; BRCOX; Peroxisomal branched chain acyl CoA oxidase; THCA CoA oxidase; THCCox; Trihydroxycoprostanoyl CoA oxidase; 3 alpha 7 alpha 12 alpha trihydroxy 5 beta cholestanoyl CoA oxidase; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholestanoyl CoA 24 hydroxylase; ACOX2_HUMAN.  
Research Area Tumour  Cell biology  immunology  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat,  (predicted: Human, Cow, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 77kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ACOX2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009]

Function:
Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids.

Subunit:
Heterodimer

Subcellular Location:
Peroxisome.

Tissue Specificity:
Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.

Similarity:
Belongs to the acyl-CoA oxidase family

Database links:

Entrez Gene: 8309 Human

Entrez Gene: 514969 Cow

Entrez Gene: 93732 Mouse

Entrez Gene: 252898 Rat

Omim: 601641 Human

SwissProt: Q99424 Human

SwissProt: Q9QXD1 Mouse

SwissProt: O02767 Rabbit

SwissProt: P97562 Rat

Unigene: 444959 Human

Unigene: 28700 Mouse

Unigene: 10622 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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