Product Name	Anti-CROT/AF350
Chinese Name	AF350标记的肉碱氧位甲基转移酶抗体
Alias	Carnitine O octanoyltransferase; COT; CROT; OCTC_HUMAN; Peroxisomal carnitine acyltransferase; Peroxisomal carnitine O octanoyltransferase; Peroxisomal carnitine O-octanoyltransferase.
Research Area	Cardiovascular  Cell biology  immunology  Chromatin and nuclear signals  Signal transduction  Cell type markers  Lipoprotein  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Dog, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CROT
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: CROT (Carnitine O-octanoyltransferase) is involved in the beta-oxidation of fatty acids. It catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. It has highest activity towards the C6 to C10 chain length substrate. It is a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria. Function: Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester. Subunit: Monomer (Probable). Subcellular Location: Peroxisome. Similarity: Belongs to the carnitine/choline acetyltransferase family. Database links: Entrez Gene: 54677 Human Entrez Gene: 74114 Mouse Omim: 606090 Human SwissProt: Q9UKG9 Human SwissProt: Q9DC50 Mouse Unigene: 125039 Human Unigene: 28197 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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