Product Name	Anti-DHX29/AF350
Chinese Name	AF350标记的ATP-依赖的RNA解旋酶29抗体
Alias	DDX29; DHX29_HUMAN; DEAH (Asp Glu Ala Asp/His) box polypeptide 29; DEAH (Asp Glu Ala His) box polypeptide 29; DEAH box protein 29; Nucleic acid helicase DDXx; Putative ATP dependent RNA helicase DHX29.
Research Area	Cell biology  transcriptional regulatory factor  Binding protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, Chimpanzee, Gorilla, Chinese Hamster)
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	155kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DHX29
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: DDX29 is a 1,369 amino acid protein encoded by the human gene DDX29. This protein belongs to the DEAD box helicase family (DEAH subfamily) and contains one helicase ATP-binding domain and one helicase C-terminal domain. DDX29 is a nuclear protein found on chromosome 5 that likely functions as an ATP-dependent RNA helicase. RNA helicases are highly conserved enzymes that utilize the energy derived from NTP hydrolysis to modulate the structure of RNA. RNA helicases participate in all biological processes that involve RNA, including transcription, splicing and translation. Function: DHX29 belongs to the DEAD box helicase family in the DEAH subfamily. It contains 1 helicase ATP-binding domain and 1 helicase C-terminal domain. DHX29 may be involved in ATP-dependent DNA or RNA unwinding. Subunit: Part of the 43S pre-initiation complex that contains at least Met-tRNA, EIF1, EIF1A (EIF1AX or EIF1AY), EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L, EIF3M, DHX29 and the 40S ribosomal subunit. Subcellular Location: Cytoplasmic Similarity: Belongs to the DEAD box helicase family. DEAH subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Database links: Entrez Gene: 54505 Human SwissProt: Q7Z478 Human Unigene: 593268 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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