Product Name	Anti-CHST2/AF350
Chinese Name	AF350标记的碳水化合物磺基转移酶2抗体
Alias	AI428561; AW121776; C130041E03Rik; C6ST; Carbohydrate (chondroitin 6/keratan) sulfotransferase 2; Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2; Carbohydrate sulfotransferase 2; CHST2; CHST2_HUMAN; Chts2; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2; GlcNAc6ST; GlcNAc6ST-1; Gn6st; Gn6st-1; GST 2; GST-2; GST2; N-acetylglucosamine 6-O-sulfotransferase 1; N-acetylglucosamine 6-O-sulfotransferase.
Research Area
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	57kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CHST2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This locus encodes a sulfotransferase protein. The encoded enzyme catalyzes the sulfation of a nonreducing N-acetylglucosamine residue, and may play a role in biosynthesis of 6-sulfosialyl Lewis X antigen. [provided by RefSeq, Aug 2011] Function: Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as L-selectin ligands. L-selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of L-selectin ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains. Subcellular Location: Golgi apparatus; trans-Golgi network membrane. Tissue Specificity: Widely expressed. Highly expressed in bone marrow, peripheral blood leukocytes, spleen, brain, spinal cord, ovary and placenta. Expressed by high endothelial cells (HEVs) and leukocytes. Similarity: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily. Database links: Entrez Gene: 9435 Human Omim: 603798 Human SwissProt: Q9Y4C5 Human Unigene: 8786 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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