Product Name	Anti-OAZ1/AF350
Chinese Name	AF350标记的鸟氨酸脱羧酶抗酶1抗体
Alias	Antizyme 1; Antizyme; AZI; MGC138338; OAZ 1; OAZ; OAZ1; OAZ1_HUMAN; ODC Az; ODC-Az; Ornithine decarboxylase antizyme 1; Ornithine decarboxylase antizyme.
Research Area	Tumour  Cell biology  immunology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	25kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human OAZ1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	Function: Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. Subunit: Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome. Similarity: Belongs to the ODC antizyme family. Database links: Entrez Gene: 4946 Human Entrez Gene: 18245 Mouse Entrez Gene: 25502 Rat Omim: 601579 Human SwissProt: P54368 Human SwissProt: P54369 Mouse SwissProt: P54370 Rat Unigene: 446427 Human Unigene: 398119 Mouse Unigene: 266 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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