Product Name	Anti-GBP6/AF350
Chinese Name	AF350标记的G蛋白Binding protein6体
Alias	DKFZp686G0786; FLJ39135; GBP 6; GBP-6; GBP6; GBP6_HUMAN; GTP binding protein 6; GTP-binding protein 6; Guanine nucleotide binding protein 6; Guanine nucleotide-binding protein 6; Guanylate binding protein 6; Guanylate binding protein family member 6; Guanylate-binding protein 6; GTP-binding protein 6.
Research Area	Tumour  Cell biology  Neurobiology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	72kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GBP6
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: GBP6 is a 633 amino acid protein that exists as two alternatively spliced isoforms belonging to the GBP family. GBP6 binds GTP, GDP and GMP, and is encoded by a gene that maps to human chromosome 1p22.2. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: Binds GTP, GDP and GMP. Similarity: Belongs to the GBP family. Database links: UniProtKB/Swiss-Prot: Q6ZN66.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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