Product Name	Anti-PP14/AF350
Chinese Name	AF350标记的胎盘蛋白14抗体
Alias	Placental protein 14; alpha uterine protein; Pregnancy-associated endometrial alpha-2 globulin; GD; GdA; GdF; GdS; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PAEP protein; PEG; PEP; PP14; Pregnancy associated endometrial alpha 2 globulin; Progestagen associated endometrial protein (placental protein 14); Progestagen associated endometrial protein; Progesterone associated endometrial protein; MGC138509; MGC142288; PAEP_HUMAN.
Research Area	Tumour  immunology  transcriptional regulatory factor  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	21kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Glycodelin A/PP14
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq, Jul 2008]. Function: This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Subunit: Homodimer. Subcellular Location: Secreted. Post-translational modifications: At least two differentially glycosylated forms are found. Glycodelin-A (GdA) (amniotic fluid) with contraceptive and immunosuppressive activities and glycodelin-S (Gds) (seminal plasma) whose role is not yet known. The gender-specific glycosylation may serve to regulate key process involved in human reproduction. Similarity: Belongs to the calycin superfamily. Lipocalin family. Database links: Entrez Gene: 5047 Human Omim: 173310 Human SwissProt: P09466 Human Unigene: 532325 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胎盘蛋白质14又称黄体激素子宫内膜癌相关蛋白。 胎盘蛋白质14是胎盘球蛋白的一种，该蛋白是子宫内膜分泌较高的黄体激素，目前多用于子宫内膜癌的研究

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