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Rabbit Anti-TGN46 antibody
Rabbit Anti-TGN46 antibody
TGN 46; TGN 51; TGN38; TGN38 homolog; TGN38B; TGN46; TGN48; TGN51; TGOLN2; TGON2_HUMAN; Trans Golgi network integral membrane protein 2; Trans golgi network protein 2; Trans Golgi network protein TGN51; Trans-Golgi network integral membrane protein 1; Tra
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Product Name TGN46
Chinese Name 高尔基体网络整合膜蛋白Recombinant rabbit monoclonal anti
Alias TGN 46; TGN 51; TGN38; TGN38 homolog; TGN38B; TGN46; TGN48; TGN51; TGOLN2; TGON2_HUMAN; Trans Golgi network integral membrane protein 2; Trans golgi network protein 2; Trans Golgi network protein TGN51; Trans-Golgi network integral membrane protein 1; Trans-Golgi network integral membrane protein 2; Trans-Golgi network protein TGN51; TTGN2.  
Immunogen Species Rabbit
Clonality Monoclonal
React Species Human,  (predicted: Mouse, )
Applications WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Form Lyophilized or Liquid
Concentration 1mg/ml
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Function:
May be involved in regulating membrane traffic to and from trans-Golgi network.

Subcellular Location:
Cell membrane. Golgi apparatus > trans-Golgi network membrane. Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.

Tissue Specificity:
Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells.

SWISS:
O43493

Gene ID:
10618

Database links:

Entrez Gene: 10618 Human

Entrez Gene: 192152 Rat

Omim: 603062 Human

SwissProt: O43493 Human

Unigene: 593382 Human

Unigene: 11349 Rat



Product Picture
Sample:
Lane 1: Human MCF-7 cell lysates
Lane 2: Human MDA-MB-231 cell lysates
Lane 3: Human HeLa cell lysates
Lane 4: Human HepG2 cell lysates
Lane 5: Human U251 cell lysates
Lane 6: Human A549 cell lysates
Primary: Anti-TGN46 (SLM-54769R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: kDa
Observed band size: 95 kDa

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