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Product Name phospho-BRD2 (Ser37) Chinese Name 磷酸化BRD2蛋白Recombinant rabbit monoclonal anti Alias Bromodomain-containing protein 2; KIAA9001; RING3; O27.1.1; Really interesting new gene 3 protein; BRD2_HUMAN; Product Type Phosphorylated anti Recombinant rabbit monoclonal anti Immunogen Species Rabbit Clonality Monoclonal Clone NO. R1A12 Applications WB=1:2000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 88kDa Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human phospho-BRD2 (Ser37) Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Subcellular Location:
Nucleus.
SWISS:
P25440
Gene ID:
6046
Database links:Entrez Gene: 6046 Human
SwissProt: P25440 Human
Product Picture Blocking buffer: 5% NFDM/TBST
Primary Ab dilution: 1:20000
Primary Ab incubation condition: 2 hours at
room temperature
Secondary Ab: Goat Anti-Rabbit IgG H&L
(HRP)
Lysate: 1: HEK-293T, 2: HEK-293T + Calyculin
A (100 nM, 60 min)
Protein loading quantity: 20 μg
Exposure time: 60 s
Predicted MW: 88 kDa
Observed MW: 110 kDa
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