Product Name	TIGIT
Chinese Name	TIGIT抗体
Alias	T-cell immunoreceptor with Ig and ITIM domains; VSIG9; VSTM3; V-set and immunoglobulin domain-containing protein 9; V-set and immunoglobulin domain-containing protein 3; TIGIT_HUMAN;
Research Area	Tumour  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	26kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinant human TIGIT protein: 22-141/244 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009] SWISS: Q495A1 Gene ID: 201633 Database links: Entrez Gene: 201633 Human Omim: 612859 Human SwissProt: Q495A1 Human Unigene: 421750 Human
Product Picture	Sample: Lane 1: Mouse Thymus tissue lysates Lane 2: Rat Lymph node tissue lysates Primary: Anti-TIGIT (SL43033R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kDa Observed band size: 35 kDa Measured by its binding ability in a indirect ELISA. Immobilized Human TIGIT protein, HisTag (Cat. SL43033P) at 2 μg/mL (100 μL/well) can bind Rabbit Anti-Human TIGIT Antibody, the EC50 is 152.5 ng/mL. Measured by its binding ability in a indirect ELISA. Immobilized Human TIGIT protein, His Tag (Cat. SL43033P) at 2 μg/mL (100 μL/well) can bind  Rabbit Anti-Human TIGIT Antibody, the EC50 is 1070 ng/mL.

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