Product Name	SPINK1
Chinese Name	Tumour相关胰蛋白酶抑制剂1Recombinant rabbit monoclonal anti
Alias	ISK1_HUMAN; Serine protease inhibitor Kazal-type 1; Pancreatic secretory trypsin inhibitor; PCTT; PSTI; TCP; TATI; Serine protease inhibitor Kazal type 1; Spink 3; Spink3; Tumor-associated trypsin inhibitor (TATI);
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	E5F9
React Species	(predicted: Human, )
Applications	IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	6.2kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG
Purification	Affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008] Subcellular Location: Secreted. SWISS: P00995 Gene ID: 6690 Database links: Entrez Gene: 6690 Human SwissProt: P00995 Human 丝氨酸蛋白酶抑制剂因子Kazal 1型(SPINK1)是蛋白酶抑制剂家族的成员之一。因其在卵巢癌，胰腺癌，肝细胞癌，结直肠癌，前列腺癌等恶性Tumour的发生、发展及预后中发挥重要作用，因此，SPINK1作为一种TumourMaker的临床应用受到广泛关注。
Product Picture	Tissue: Human pancreas Section type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000 Primary ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Comment: Color brown is the positive signal for SLM-60323R

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