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Product Name Parvalbumin Chinese Name Immunogen Species Mouse Clonality Monoclonal Clone NO. F4D8 React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:1000 IHC-P=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization The nucleus The cell membrane Form Liquid Concentration 1mg/ml Lsotype IgG1/Kappa Purification Affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Parvalbumin是一种小而稳定的蛋白质,含有EF手型钙结合位点。它参与钙信号传导。通常,这种蛋白质被分成三个结构域:AB、CD和EF,每个域分别包含一个螺旋-环-螺旋基序。[2]AB结构域在环区域包含两个氨基酸缺失,而域CD和EF分别包含N-末端和C-末端。钙Binding proteinparvalbumin在许多生理过程中发挥作用,即细胞周期调节、第二信使产生、肌肉收缩、微管组织和光传导。因此,钙Binding protein必须在高浓度的其他金属离子存在下区分钙。钙的选择性机理已被广泛研究。
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