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Product Name Arginase2 Chinese Name Immunogen Species Mouse Clonality Monoclonal Clone NO. C8A5 React Species (predicted: Mouse, Rat, ) Applications WB=1:1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization The cell membrane Form Liquid Concentration 1mg/ml Lsotype IgG1/kappa Purification Affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail 可能在调节尿素循环外精氨酸代谢和降低一氧化氮合成中发挥作用。精氨酸代谢是先天性和适应性免疫反应的重要调节因子。似乎参与了活化CD4+和CD8+T细胞存活能力的负调节。也可抑制哮喘气道上皮炎症相关信号传导。还可能通过限制M1巨噬细胞活化和多胺代谢而导致H.pylori免疫逃避。在胎儿中,树突状细胞可能在妊娠期促进免疫抑制和T细胞TNF-α的产生。调节RPS6KB1信号传导,可以促进endothelial cells衰老和炎症,并影响NOS3/eNOS功能障碍。 Product Picture
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