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Mouse Anti-HDAC8 antibody
Mouse Anti-HDAC8 antibody
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Details

Product Name HDAC8
Chinese Name
Immunogen Species Mouse
Clonality Monoclonal
Clone NO. A6A2
React Species (predicted: Human, )
Applications WB=1:1000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Cellular localization The nucleus The cell membrane 
Form Liquid
Concentration 1mg/ml
Lsotype IgG1/Kappa
Purification Affinity purified by Protein G
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail 负责核心组蛋白(H2A、H2B、H3和H4)N端赖氨酸残基的脱乙酰。组蛋白去乙酰化为表观遗传抑制提供了一个标签,在转录调控、细胞周期进展和发育事件中起着重要作用。组蛋白脱乙酰基酶通过形成大的多蛋白复合物起作用。也参与粘蛋白复合物蛋白SMC3的脱乙酰化,调节染色质中粘蛋白复合物的释放。可能在平滑肌细胞收缩中起作用。
Product Picture
Blocking buffer: 5% NFDM/TBST
Primary ab dilution: 1:1000
Primary ab incubation condition: 2 hours at room temperature
Lysate: HeLa, MCF-7, HepG2, A549, Daudi
Protein loading quantity: 20 μg
Exposure time: 60 s
Predicted MW: 40 kDa
Observed MW: 40 kDa

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