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Product Name HDAC8 Chinese Name Immunogen Species Mouse Clonality Monoclonal Clone NO. A6A2 React Species (predicted: Human, ) Applications WB=1:1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization The nucleus The cell membrane Form Liquid Concentration 1mg/ml Lsotype IgG1/Kappa Purification Affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail 负责核心组蛋白(H2A、H2B、H3和H4)N端赖氨酸残基的脱乙酰。组蛋白去乙酰化为表观遗传抑制提供了一个标签,在转录调控、细胞周期进展和发育事件中起着重要作用。组蛋白脱乙酰基酶通过形成大的多蛋白复合物起作用。也参与粘蛋白复合物蛋白SMC3的脱乙酰化,调节染色质中粘蛋白复合物的释放。可能在平滑肌细胞收缩中起作用。 Product Picture
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