Product Name	COX1/MTCO1
Chinese Name	细胞色素c氧化酶1单克隆抗体
Alias	COX1_HUMAN; Cytochrome c oxidase subunit 1; EC:7.1.1.9; Cytochrome c oxidase polypeptide I; MT-CO1; COI; COXI; COX I; MTCO1;
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	E7A11
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:1000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG
Purification	Affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Contributes to cytochrome-c oxidase activity. Predicted to be involved in electron transport coupled proton transport and mitochondrial electron transport, cytochrome c to oxygen. Part of mitochondrial respiratory chain complex III and mitochondrial respiratory chain complex IV. [provided by Alliance of Genome Resources, Apr 2022] Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. SWISS: P00395 Gene ID: 4512 Database links: Entrez Gene: 4512 Human Entrez Gene: 17708 Mouse Entrez Gene: 26195 Rat SwissProt: P00395 Human SwissProt: P00397 Mouse SwissProt: P05503 Rat 细胞色素c氧化酶的组成部分，是Mitochondrion电子传递链中最后一个推动氧化磷酸化的酶。呼吸链包含3个多亚单位复合物琥珀酸脱氢酶（复合体II，CII）、泛醌细胞色素c氧化还原酶（细胞色素b-c1复合物，复合体III，CIII）和细胞色素c氧化酶（复合体IV，CIV），它们协同将NADH和琥珀酸衍生的电子转移到分子氧中，在内膜上形成一个电化学梯度来驱动跨膜转运和ATP合成酶。
Product Picture	Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 2 hours at room temperature Lysate: HeLa, MCF-7, N2a, BRL Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 57 kDa Observed MW: 35 kDa

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