TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Aquaporin 4 Chinese Name 水Channel protein4单克隆抗体 Alias aquaporin 4; WCH4; Mercurial-insensitive water channel; MIWC; AQP 4; AQP4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; MGC22454; MIWC; AQP4_HUMAN; Aquaporin-4; AQP-4. Research Area Tumour Signal transduction Channel protein The new supersedes the old Immunogen Species Mouse Clonality Monoclonal Clone NO. 6G1 React Species Human, Mouse, Rat, Applications ELISA=1:1000-5000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 36kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen Recombinant human Aquaporin 4 Protein Lsotype IgG1 Purification affinity purified by Protein G Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Subunit:
Homotetramer. Part of a complex containing MLC1, TRPV4, HEPACAM and ATP1B1.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Brain, muscle, heart, kidney, lung, and trachea.
Similarity:
Belongs to the MIP/aquaporin (TC 1.A.8) family.
SWISS:
P55087
Gene ID:
361
Database links:
Entrez Gene: 361 Human
Entrez Gene: 11829 Mouse
Omim: 600308 Human
SwissProt: P55087 Human
SwissProt: P55088 Mouse
Unigene: 281008 Cow
Unigene: 315369 Human
Unigene: 250786 Mouse
Unigene: 90091 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (Human lung cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Aquaporin 4) Monoclonal Antibody, Unconjugated (SLM-33068M) at 1:800 overnight at 4°C, followed by operating according to SP Kit(Mouse) (sp-0024) instructions and DAB staining.Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Aquaporin 4) Monoclonal Antibody, Unconjugated (SLM-33068M) at 1:800 overnight at 4°C, followed by operating according to SP Kit(Mouse) (sp-0024) instructions and DAB staining.Paraformaldehyde-fixed, paraffin embedded (mouse lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Aquaporin 4) Monoclonal Antibody, Unconjugated (ascites of SLM-33068M 6G1) at 1:2000 overnight at 4°C, followed by operating according to SP Kit(Mouse) (sp-0024) instructions and DAB staining.
Scan Wechat Qrcode