Product Name	Methamphetamine
Chinese Name	甲基苯丙胺（冰毒）单克隆抗体
Alias	d-Desoxyephedrine hydrochloride; d-N; α-Dimethylphenethylamine hydrochloride; Methylamphetamine hydrochloride; METH.
Immunogen Species	Mouse
Clonality	Monoclonal
Applications	ELISA=1:5000-10000 ICA=  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	0.18569kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
Lsotype	IgG
Purification	affinity purified by Protein G
Buffer Solution	0.01M TBS(pH7.4)
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.

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