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Product Name CGA Chinese Name 人绒毛膜促性腺激素α 亚基单抗 Alias GLHA_HUMAN; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha (CG-alpha); Follicle-stimulating hormone alpha chain (FSH-alpha); Follitropin alpha chain; Luteinizing hormone alpha chain (LSH-alpha); Lutropin alpha chain; Thyroid-stimulating hormone alpha chain (TSH-alpha); Thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; HCG alpha; Research Area Tumour immunology Immunogen Species Mouse Clonality Monoclonal Clone NO. 4A8 React Species Human, Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 10kDa Form Liquid Concentration 1mg/ml immunogen Natural human hCG protein Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M PBS(pH7.4) with 0.03% Proclin300 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Function:
Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
Subcellular Location:
Secreted.
Similarity:
Belongs to the glycoprotein hormones subunit alpha family.
SWISS:
P01215
Gene ID:
1081
Database links:Entrez Gene: 1081 Human
SwissProt: P01215 Human
HCG是由胎盘合体滋养层细胞产生的一种glycoprotein激素,主要用于胎盘滋养细胞和生殖细胞Tumour如葡萄胎、绒癌的诊断和辅助诊断。Product Picture
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