Product Name	PAR3
Chinese Name	蛋白酶激活受体3抗体
Alias	Proteinase Activated Receptor 3; coagulation factor II (thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Thrombin receptor-like 2.
literatures	Specific References  (2)     |     SL9510R has been referenced in 2 publications. [IF=2.272] Liu et al. Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer. (2016) Onco.Targets.Ther. 9:4121-7  WB ;  Human.   PubMed:27462166 [IF=1.56] Huang, Chao, et al. "Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis. Corrigendum in/10.3892/mmr. 2016.5882." Molecular Medicine Reports 14.3 (2016): 2555-2565.  IHC-P ;  Human.   PubMed:27484148
Research Area	Cardiovascular  Cell biology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	42kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PAR3: 121-220/374 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. Tissue specificity: Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. Function: Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. Subcellular Location: Cell membrane. Tissue Specificity: Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. Post-translational modifications: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: O00254 Gene ID: 2151 Database links: Entrez Gene: 2151 Human Omim: 601919 Human SwissProt: Q58D85 Cow SwissProt: O00254 Human Unigene: 24447 Cow Unigene: 136948 Human Unigene: 42502 Human
Product Picture	Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- PAR3 (SL9510R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 57 kD

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