Product Name	SLC47A1
Chinese Name	溶质载体蛋白家族47成员A1抗体
Alias	1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.
literatures	Specific References  (1)     |     SL9284R has been referenced in 1 publications. [IF=6.208] Muhammad Erfan Uddin. et al. MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia. INT J MOL SCI. 2022 Jan;23(15):8607  IHC ;  Mouse.   PubMed:35955741
Research Area	Tumour  Cell biology  Signal transduction  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	58kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC47A1: 211-310/530
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008] Function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. Subcellular Location: Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles. Tissue Specificity: Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes). Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. SWISS: Q96FL8 Gene ID: 55244 Database links: Entrez Gene: 55244 Human Omim: 609832 Human SwissProt: Q96FL8 Human Unigene: 232054 Human
Product Picture	Sample: 293T Cell (Human) Lysate at 40 ug Adrenal gand (Mouse) Lysate at 40 ug Primary: Anti-SLC47A1 (SL9284R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 62 kD Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC47A1) Polyclonal Antibody, Unconjugated (SL9284R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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