TEL: +86 571 56623320 EMAIL: [email protected]
Product Name FBXO24 Chinese Name FBXO24蛋白抗体 Alias F box only protein 24; F box protein 24; F box protein Fbx24; F-box only protein 24; FBX24; FBX24_HUMAN; FBXO24. Research Area Cell biology immunology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 65kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FBXO24: 331-430/580 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FBXO24 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation dependent ubiquitination. There are 2 isoforms produced by alternative splicing.
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
Subunit:
Directly interacts with SKP1 and CUL1 (By similarity).
Similarity:
Contains 1 F-box domain.
Contains 1 RCC1 repeat.
SWISS:
O75426
Gene ID:
26261
Database links:Entrez Gene: 26261 Human
Entrez Gene: 71176 Mouse
Omim: 609097 Human
SwissProt: O75426 Human
SwissProt: Q9D417 Mouse
Unigene: 283764 Human
Unigene: 474695 Mouse
Scan Wechat Qrcode