Product Name	FBXO27
Chinese Name	FBXO27蛋白抗体
Alias	F-box G-domain protein 5; F-box only protein 27; F-box protein 27; F-box protein FBG5; FBG5; Fbx27.
Research Area	Cell biology  immunology  Signal transduction  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	32kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FBXO27: 201-283/283
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin (CUL1), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Subunit: Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with SKP1 and CUL1. Tissue Specificity: Predominantly expressed in brain, heart and kidney. Expressed at lower levels in liver and lung. Similarity: Contains 1 F-box domain. Contains 1 FBA (F-box associated) domain. SWISS: Q8NI29 Gene ID: 126433 Database links: Entrez Gene: 126433 Human Entrez Gene: 233040 Mouse Omim: 609099 Human SwissProt: Q8NI29 Human SwissProt: Q6DIA9 Mouse Unigene: 187461 Human

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