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Product Name FBXO28 Chinese Name FBXO28蛋白抗体 Alias F box only protein 28; F box protein 28; Fbx28; FLJ10766; KIAA0483; OTTHUMP00000035597; FBX28_HUMAN. Research Area Cell biology immunology Cyclin Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 41kDa Cellular localization The nucleus cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FBXO25: 301-368/368 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FBXO28 is a member of the F-box protein family. Such proteins are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases.
Function:
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation (By similarity).
Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity).
Similarity:
Contains 1 F-box domain.
SWISS:
Q9NVF7
Gene ID:
23219
Database links:Entrez Gene: 23219 Human
Entrez Gene: 67948 Mouse
Omim: 609100 Human
SwissProt: Q9NVF7 Human
SwissProt: Q8BIG4 Mouse
Unigene: 64691 Human
Unigene: 713992 Human
Unigene: 30737 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FBXO28) Polyclonal Antibody, Unconjugated (SL9088R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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