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Product Name CKI gamma 3 Chinese Name 酪蛋白激酶1γ3/CKI γ3抗体 Alias CKI gamma 3; casein kinase 1 gamma 3; Casein kinase I isoform gamma 3; Casein kinase I isoform gamma-3; CKI-gamma 3; Csnk1g3; KC1G3_HUMAN. Research Area Cell biology immunology Signal transduction Cyclin Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 51kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CKI gamma 3: 151-250/447 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.
Function:
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).
Subunit:
Monomer.
Subcellular Location:
Cytoplasm
Post-translational modifications:
Autophosphorylated.
Similarity:
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Contains 1 protein kinase domain.
SWISS:
Q9Y6M4
Gene ID:
1456
Database links:Entrez Gene: 1456 Human
Omim: 604253 Human
SwissProt: Q9Y6M4 Human
Unigene: 129206 Human
Unigene: 10084 Rat
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