Product Name	AKAP2/PALM2
Chinese Name	蛋白激酶A2抗体
Alias	A kinase (PRKA) anchor protein 2; A kinase anchor protein 2; AKAP 2; AKAP KL; AKAPKL; KIAA0920; PALM 2; PALM2; PRKA 2; PRKA2; Protein kinase A anchoring protein 2; Protein kinase A2; AKAP2_HUMAN.
literatures	Specific References  (1)     |     SL9028R has been referenced in 1 publications. [IF=4.147] Bing Wang. et al. AKAP2 overexpression modulates growth plate chondrocyte functions through ERK1/2 signaling. Bone. 2021 May;146:115875  WB,IF ;  Human.   PubMed:33571699
Research Area	Cell biology  immunology  Signal transduction  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	95kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human AKAP2: 151-250/859
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	AKAP2 binds to regulatory subunit (RII) of protein kinase A and can be differentially expressed as a natural AKAP2-PALM2 chimeric protein. It may be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. There are 2 named isoforms produced by alternative splicing. Function: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). SWISS: Q9Y2D5 Gene ID: 11217 Database links: Entrez Gene: 11217 Human Omim: 604582 Human SwissProt: Q9Y2D5 Human

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