Product Name	IFNA1
Chinese Name	Interferonα抗体
Alias	Interferon alpha 1b; IFab; IFN alpha 1b; IFN-alpha 1b; IFN-α1; IFN-α1b; IFN a1b; Interferon alpha-1/13; IFN-alpha-1/13; Interferon alpha-D; LeIF D; IFNA1_HUMAN; IFNA1; IFNA13; IFNA1_MOUSE.
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	19kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse IFN-Alpha: 121-189/189
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The genes encoding type I interferons (IFNs), which include 14 IFN-alphagenes (two of which are IFN-alpha1 and IFN-alpha13), one IFN-∫ gene, one IFN-w (also known as IFN-alpha II1) gene and a number of IFN-w pseudogenes, are clustered on human chromosome 9. IFN-alpha and -beta are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-alpha, IFN-beta or IFN-gamma, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-alphaR) interacts with IFN-alpha, IFN-beta and IFN-w, and seems to be a multisubunit receptor. Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Subcellular Location: Secreted. Similarity: Belongs to the alpha/beta interferon family. SWISS: P01572 Gene ID: 15962 Database links: Entrez Gene: 15962 Mouse Entrez Gene: 230396 Mouse SwissProt: P01572 Mouse
Product Picture	Tissue/cell: mouse intestine tissue;4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-IFN-Alpha Polyclonal Antibody, Unconjugated(SL8995R) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(SL0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C. DAPI(5ug/ml,blue,C-0033) was used to stain the cell nuclei

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