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Product Name Phostensin Chinese Name 蛋白磷酸酶1调节亚单位18抗体 Alias HKMT1098; KIAA1949; PPP1R18; Protein phosphatase 1 F actin cytoskeleton targeting subunit; Protein phosphatase 1 regulatory subunit 18. Research Area Cell biology Signal transduction Binding protein Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Pig, ) Applications WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 68kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Phostensin: 101-200/613 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008]
Subunit:
Interacts with Protein phosphatase 1 (PP1).
Subcellular Location:
Cytoplasm; cytoskeleton.
SWISS:
Q6NYC8
Gene ID:
170954
Database links:Entrez Gene: 100051083 Horse
Entrez Gene: 170954 Human
Omim: 610990 Human
SwissProt: Q6NYC8 Human
Unigene: 101150 Human
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