Product Name	Pancreatic hormone
Chinese Name	胰腺激素抗体
Alias	Pancreatic hormone precursor; Pancreatic polypeptide Y; Pancreatic prohormone; Pancreatic prohormone precursor; PNP; PP; PPY; Pancreatic prohormone; Pancreatic polypeptide; PP; INN=Obinepitide; Pancreatic hormone; PH; Pancreatic icosapeptide; PI; PAHO_HUMAN.
literatures	Specific References  (1)     |     SL8543R has been referenced in 1 publications. [IF=2.694] Kate L. Lee. et al. Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes. 2021 Oct 09  IHC ;  Mouse.   PubMed:34632959
Research Area	Neurobiology  Signal transduction  Growth factors and hormones  Diabetes
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	4kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Pancreatic hormone: 30-65/95
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Function: Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. The physiological role for the icosapeptide has not yet been elucidated. Subunit: Belongs to the NPY family. Subcellular Location: Secreted. Similarity: Belongs to the NPY family. SWISS: P01298 Gene ID: 5539 Database links: Entrez Gene: 5539 Human Omim: 167780 Human SwissProt: P01298 Human Unigene: 558368 Human
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Pancreatic hormone) Polyclonal Antibody, Unconjugated (SL8543R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.

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