Product Name	RFPL2+RFPL3
Chinese Name	RET指蛋白样2/3抗体
Alias	RFPL2 + RFPL3; Ret finger protein like 3; ret finger protein-like 3; RFPL 3; RFPL3; RFPL-3; RFPL2_HUMAN.
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	42kDa
Cellular localization	The nucleus The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RFPL3: 141-240/378
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The RFPL3 protein is 371 amino acids long and may have been emerged due to intrachromosomal duplication.RFPL1, RFPL2 and RFPL3 (ret finger protein-like 1, 2 and 3, respectively), exist as a cluster of genes mapping to human chromosome 22q12.2-q13.3, sharing 95%-96% identity. RFPL1, 2 and 3, are thought to contribute to neocortex organization and size in primates, and show high expression in fetal neocortex as well as embryonic stem-cell neurogenesis. Each of the three RFPL genes encodes two exons giving rise to a putative RING-like motifs and B30-2 domains. RFPL1, also known as RNF78 or MGC132428, is a 317 amino acid protein known to have high expression in prostate with lower expression in adult brain, fetal liver and fetal kidney. RFPL2, or RNF79, is 378 amino acids long and is also highly expressed in prostate with lower expression in fetal kidney and fetal liver. As a result of alternative splicing, three isoforms of RFPL2 exist. Tissue Specificity: Seems to be expressed in prostate and less abundantly in adult brain, fetal liver, and fetal kidney. Similarity: Contains 1 B30.2/SPRY domain. Contains 1 RING-type zinc finger. SWISS: O75678 Gene ID: 10739 Database links: Entrez Gene: 10739 Human Omim: 605969 Human SwissProt: O75678 Human Unigene: 157427 Human
Product Picture	Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti- RFPL2+RFPL3 (SL8493R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 45 kD

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