Product Name	FBXL17
Chinese Name	FBXL17蛋白抗体
Alias	F box and leucine rich repeat protein 17; F box only protein 13; F box/LRR repeat protein 17; F-box and leucine-rich repeat protein 17; F-box only protein 13; F-box/LRR-repeat protein 17; FBL17; FBX13; Fbxl17; FBXO13; FBXL13; FXL17_HUMAN; DKFZP434C1715.
Research Area	Cell biology  immunology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	76kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FBXL17: 451-550/701
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Subunit: Interacts with SKP1 and CUL1 Similarity: Contains 1 F-box domain. SWISS: Q9UF56 Gene ID: 64839 Database links: Entrez Gene: 64839 Human Entrez Gene: 50758 Mouse Entrez Gene: 316663 Rat Omim: 609083 Human SwissProt: Q9UF56 Human SwissProt: Q9QZN1 Mouse Unigene: 657225 Human Unigene: 721914 Human Unigene: 136366 Mouse
Product Picture	Sample: MDA-MB-231 cell (Human) Lysate at 30 ug Primary: Anti-FBXL17 (SL8469R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 76kD Observed band size: 76kD

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