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Product Name SERPINB13 Chinese Name 丝氨酸蛋白酶抑制剂13抗体 Alias HaCaT UV-repressible serpin; Headpin; HSHUR7SEQ; HUR7; Hurpin; serpinB13; Peptidase inhibitor 13; PI-13; PI13; Protease inhibitor 13; Proteinase inhibitor 13; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 13; Serpin B13; Serpin peptidase inhibitor clade B (ovalbumin) member 13; SERPINB13; SPB13_HUMAN; UV B repressed sequence HUR 7. Research Area Cardiovascular Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 44kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Headpin/SERPINB13: 101-200/391 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Headpin is a skin-specific, UV-repressible serine proteinase inhibitor (serpin) belonging to the ovalbumin serpin family. Headpin is abundant in the human keratinocyte cell line HaCaT, and in lesional keratinocytes from psoriatic skin. Headpin downregulation occurs in squamous cell carcinoma of the oral cavity and in squamous cell carcinoma cell lines of the head and neck.
Function:
May play a role in the proliferation or differentiation of keratinocytes.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Skin specific.
Similarity:
Belongs to the serpin family. Ov-serpin subfamily.
SWISS:
Q9UIV8
Gene ID:
5275
Database links:Entrez Gene: 5275 Human
Omim: 604445 Human
SwissProt: Q9UIV8 Human
Unigene: 241407 Human
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