Product Name	Alpha casein
Chinese Name	α酪蛋白抗体
Alias	Alpha-S1-casein; CASA; CASA1_HUMAN; Casein alpha s1; Casoxin-D; CSN1; CSN1S1.
literatures	Specific References  (4)     |     SL8245R has been referenced in 4 publications. [IF=3.86] Chu, Meiqiang, et al. "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." Molecular and Cellular Endocrinology (2017).  WB ;  Human.   PubMed:28599789 [IF=3.571] Yu M et al. Taurine promotes milk synthesis via the GPR87-PI3K-SETD1A signaling in BMECs. J Agric Food Chem. 2019 Feb 20;67(7):1927-1936.  WB ;  Mouse.   PubMed:30678459 [IF=3.412] Qi H et al. Methionine Promotes Milk Protein and Fat Synthesis and Cell Proliferation via the SNAT2-PI3K Signaling Pathway in Bovine Mammary Epithelial Cells.(2018) J Agric Food Chem.66(42):11027-11033.  WB ;  dairy cow.   PubMed:30274521 [IF=1.487] Mengmeng Yu. et al. Daidzein promotes milk synthesis and proliferation of mammary epithelial cells via the estrogen receptor α-dependent NFκB1 activation. 2020 May 13  WB ;  Bovine.   PubMed:32401613
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	28kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Alpha casein: 31-130/185
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Important role in the capacity of milk to transport calcium phosphate. Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1. Subunit: Heteromultimers of alpha-s1 casein and kappa-casein; disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Mammary gland specific. Secreted in milk. Similarity: Belongs to the alpha-casein family. SWISS: P47710 Gene ID: 1446 Database links: Entrez Gene: 1446 Human Omim: 115450 Human SwissProt: P47710 Human Unigene: 3155 Human
Product Picture	Sample: Human breast milk Lysate at 2 uL Human breast milk Lysate at 6 uL Human breast milk Lysate at 8 uL Primary: Anti-Alpha casein (SL8245R) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 21 kD Sample: Lane 1: Human Milk lysates Primary: Anti-Alpha casein (SL8245R) at 1/200 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kDa Observed band size: 24 kDa

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