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Rabbit Anti-CUEDC1 antibody
Rabbit Anti-CUEDC1 antibody
CUE domain containing protein 1; CUED1_HUMAN.
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Regular members: $334.4
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  • NO.:SL8243R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Zebrafish,Sheep,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
  • Goods click count:20
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Details

Product Name CUEDC1
Chinese Name CUE结构域蛋白1抗体
Alias CUE domain containing protein 1; CUED1_HUMAN.  
Research Area Tumour  Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 42kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CUEDC1: 251-350/386 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The coupling of ubiquitin conjugation to endoplasmic reticulum (ER) degradation (CUE) domain functions as a ubiquitin (UB) binding domain that is approximately 40 amino acids in length. Present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways, CUE domains can bind monoubiquitin and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. Two isoforms of CUEDC1 exist due to alternative splicing events.

Similarity:
Contains 1 CUE domain.

SWISS:
Q9NWM3

Gene ID:
404093

Database links:

Entrez Gene: 404093 Human

Entrez Gene: 103841 Mouse

Entrez Gene: 303419 Rat

SwissProt: Q9NWM3 Human

SwissProt: Q8R3V6 Mouse

Unigene: 46679 Human



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