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Product Name FRMD2 Chinese Name FRMD2蛋白抗体 Alias FERM and PDZ domain containing protein 1; FERM domain containing protein 2; FRMD2; KIAA0967; FRPD1_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 173kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FRMD2/FRMPD1: 171-280/1578 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FRMPD1 has been identified as a regulatory binding partner of activator of G-protein signaling 3 (AGS3).
Function:
Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.
Subunit:
Interacts with GPSM1.
Subcellular Location:
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found both in the cytoplasm and associated with the cell membrane.
Similarity:
Contains 1 FERM domain.
Contains 1 PDZ (DHR) domain.
SWISS:
Q5SYB0
Gene ID:
22844
Database links:Entrez Gene: 22844 Human
SwissProt: Q5SYB0 Human
Unigene: 163990 Human
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