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Product Name GNL1 Chinese Name 鸟嘌呤核苷酸Binding protein1抗体 Alias Gnl1; GNL1_HUMAN; GTP binding protein HSR1; GTP-binding protein HSR1; Guanine nucleotide binding protein like 1; Guanine nucleotide-binding protein-like 1; HSR1; HSR1 GTP binding protein. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Monkey, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 69kDa Cellular localization The nucleus Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GNL1: 301-400/607 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008].
Function:
Possible regulatory or functional link with the histocompatibility cluster.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the MMR1/HSR1 GTP-binding protein family.
Contains 1 G (guanine nucleotide-binding) domain.
SWISS:
P36915
Gene ID:
2794
Database links:Entrez Gene: 2794 Human
Omim: 143024 Human
SwissProt: P36915 Human
SwissProt: P36916 Mouse
Unigene: 118354 Human
Unigene: 83147 Human
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