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Rabbit Anti-CNKSR1 antibody
Rabbit Anti-CNKSR1 antibody
CNK; CNK homolog protein 1; CNK1; CNKR1_HUMAN; CNKSR1; Connector enhancer of kinase suppressor of ras 1; Connector enhancer of KSR 1; Connector enhancer of KSR like; Connector enhancer of KSR-like; Connector enhancer of KSR1; hCNK1; KSR.
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  • NO.:SL8028R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name CNKSR1
Chinese Name Ras激酶抑制因子连接增强蛋白1抗体
Alias CNK; CNK homolog protein 1; CNK1; CNKR1_HUMAN; CNKSR1; Connector enhancer of kinase suppressor of ras 1; Connector enhancer of KSR 1; Connector enhancer of KSR like; Connector enhancer of KSR-like; Connector enhancer of KSR1; hCNK1; KSR.  
Research Area Cell biology  immunology  Signal transduction  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 80kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CNKSR1: 621-720/720 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway. [provided by RefSeq, Jul 2008].

Function:
May function as an adapter protein or regulator of Ras signaling pathways.

Subunit:
Interacts with RHO and RALGDS.

Subcellular Location:
Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).

Post-translational modifications:
Phosphorylated on tyrosine.

Similarity:
Belongs to the CNKSR family.
Contains 1 CRIC domain.
Contains 1 PDZ (DHR) domain.
Contains 1 PH domain.
Contains 1 SAM (sterile alpha motif) domain.

SWISS:
Q969H4

Gene ID:
10256

Database links:

Entrez Gene: 10256 Human

Entrez Gene: 194231 Mouse

Entrez Gene: 298545 Rat

Omim: 603272 Human

SwissProt: Q969H4 Human

Unigene: 16232 Human

Unigene: 726160 Human

Unigene: 331958 Mouse



Product Picture
Sample:
brain (Mouse) Lysate at 40 ug
Primary: Anti-CNKSR1 (SL8028R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 80 kD
Observed band size: 80 kD

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