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Product Name CLPTM1 Chinese Name 唇裂和腭裂相关Transmembrane protein1抗体 Alias Cleft lip and palate associated transmembrane protein 1; CLPTM 1; HS9; N14; CLPT1_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 76kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CLPTM1: 75-120/669 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Clefts of the oral-facial region usually occur in early fetal development and can affect the lip, the soft palate (the soft tissue in the back of the mouth) and the hard palate (the roof of the mouth). Cleft lip (with or without cleft palate) is a genetically complex birth defect that occurs in approximately one in every 750-1,000 live births. This is one of the most common birth defects and is multifactorial, with both genetic and environmental causes. Cleft lip- and palate-associated transmembrane protein 1 (CLPTM1) belongs to a family of cleft lip and palate transmembrane proteins. This family also contains cisplatin resistance-related protein (CRR9), which is involved in CDDP-induced apoptosis. The CLPTM1 protein shows strong homology to two Caenorhabditis elegans genes.
Function:
May play a role in T-cell development (By similarity).
Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the CLPTM1 family.
SWISS:
O96005
Gene ID:
1209
Database links:Entrez Gene: 1209 Human
Entrez Gene: 56457 Mouse
Omim: 604783 Human
SwissProt: O96005 Human
SwissProt: Q8VBZ3 Mouse
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