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Rabbit Anti-CLPTM1 antibody
Rabbit Anti-CLPTM1 antibody
Cleft lip and palate associated transmembrane protein 1; CLPTM 1; HS9; N14; CLPT1_HUMAN.
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  • NO.:SL8018R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:16
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Details

Product Name CLPTM1
Chinese Name 唇裂和腭裂相关Transmembrane protein1抗体
Alias Cleft lip and palate associated transmembrane protein 1; CLPTM 1; HS9; N14; CLPT1_HUMAN.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 76kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CLPTM1: 75-120/669 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Clefts of the oral-facial region usually occur in early fetal development and can affect the lip, the soft palate (the soft tissue in the back of the mouth) and the hard palate (the roof of the mouth). Cleft lip (with or without cleft palate) is a genetically complex birth defect that occurs in approximately one in every 750-1,000 live births. This is one of the most common birth defects and is multifactorial, with both genetic and environmental causes. Cleft lip- and palate-associated transmembrane protein 1 (CLPTM1) belongs to a family of cleft lip and palate transmembrane proteins. This family also contains cisplatin resistance-related protein (CRR9), which is involved in CDDP-induced apoptosis. The CLPTM1 protein shows strong homology to two Caenorhabditis elegans genes.

Function:
May play a role in T-cell development (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the CLPTM1 family.

SWISS:
O96005

Gene ID:
1209

Database links:

Entrez Gene: 1209 Human

Entrez Gene: 56457 Mouse

Entrez Gene: 292696 Rat

Omim: 604783 Human

SwissProt: O96005 Human

SwissProt: Q8VBZ3 Mouse



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