Product Name	WNT 5B
Chinese Name	信号通路Wnt-5B抗体
Alias	MGC2648; Wnt5b; Protein Wnt-5b; Wingless type MMTV integration site family, member 5B; WNT 5B; WNT 5B protein; Wnt5b; WNT5B protein; WNT5B_HUMAN.
Research Area	Cell biology  Signal transduction  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human WNT5B: 201-300/359
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Subunit: Interacts with PORCN. Subcellular Location: Secreted > extracellular space > extracellular matrix. Similarity: Belongs to the Wnt family. SWISS: Q9H1J7 Gene ID: 81029 Database links: Entrez Gene: 508008 Cow Entrez Gene: 486756 Dog Entrez Gene: 81029 Human Entrez Gene: 22419 Mouse Entrez Gene: 100349579 Rabbit Entrez Gene: 282582 Rat Entrez Gene: 30105 Zebrafish Omim: 606361 Human SwissProt: Q9H1J7 Human SwissProt: P22726 Mouse SwissProt: Q92050 Zebrafish Unigene: 306051 Human Unigene: 321818 Mouse Unigene: 58724 Rat Unigene: 389 Zebrafish
Product Picture	Sample:Bladder (Mouse)Lysate at 40 ug Primary: Anti- WNT 5B(SL8010R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 38kD Observed band size: 38kD

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