Product Name	CCBE1
Chinese Name	Collagen protein和钙结合表皮生长因子结构域1抗体
Alias	CCBE 1; ccbe1; CCBE1_HUMAN; Collagen and calcium binding EGF domain containing protein 1; Collagen and calcium binding EGF domains 1; Collagen and calcium-binding EGF domain-containing protein 1; Full of fluid protein homolog.
Research Area	Cell biology  immunology  Growth factors and hormones
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CCBE1: 201-300/406
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is thought to function in extracellular matrixremodeling and migration. It is predominantly expressed in theovary, but down regulated in ovarian cancer cell lines and primarycarcinomas, suggesting its role as a tumour suppressor. Mutationsin this gene have been associated with Hennekamlymphangiectasia-lymphedema syndrome, a generalized lymphaticdysplasia in humans. [provided by RefSeq, Mar 2010]. Function: Required for lymphangioblast budding and angiogenicsprouting from venous endothelium during embryogenesis. Subcellular Location: Secreted (Potential). DISEASE: Defects in CCBE1 are the cause of Hennekamlymphangiectasia-lymphedema syndrome (HLLS) [MIM:235510]. HLLS is ageneralized lymph-vessels dysplasia characterized by intestinallymphangiectasia with severe lymphedema of the limbs, genitalia andface. In addition, affected individuals have unusual facies andsevere mental retardation. Similarity: Belongs to the CCBE1 family. Contains 1 EGF-like domain. SWISS: Q6UXH8 Gene ID: 147372 Database links: Entrez Gene: 147372 Human Omim: 612753 Human SwissProt: Q6UXH8 Human Unigene: 34333 Human
Product Picture	Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti-CCBE1 (SL7985R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 49 kD

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