Product Name	SPAG8
Chinese Name	精子相关抗原8抗体
Alias	HSD 1; HSD1; hSMP1; MH SPAG8; OTTMUSP00000032209; SMP1; SPAG3; Sperm associated antigen 8; Sperm associated antigen 8 like protein; Sperm membrane protein 1; MGC26201; OTTHUMP00000021352; BS 84; SPAG8_HUMAN.
Research Area	Cell biology  immunology  Developmental biology  Stem cells  Cyclin  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SPAG8: 342-426/426
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SPAG8 is a human sperm membrane protein expressed during development and is a testis-specific component produced during male germ cell differentiation. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. Function: May play a role in fertility and microtubule formation through interaction with RANBP9. Subunit: Interacts with RANBP9. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, acrosome. Tissue Specificity: Expressed in testis (germ cells), but not in liver, kidney, prostate and small intestine. SWISS: Q99932 Gene ID: 26206 Database links: UniProtKB/Swiss-Prot: Q99932.2

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