Product Name	SCEL
Chinese Name	SCEL蛋白抗体
Alias	Scel; SCEL_HUMAN; Sciellin; FLJ21667; MGC22531.
Research Area	Cell biology  Signal transduction  Cyclin  Cell type markers  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	78kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SCEL: 581-688/688
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope. Tissue specificity:Highly expressed in esophagus. It is also expressed in keratinocytes, amniotic tissue, foreskin stratum spinosum and stratum granulosum, hair follicle and nail. Function: May function in the assembly or regulation of proteinsin the cornified envelope. The LIM domain may be involved inhomotypic or heterotypic associations and may function to localizesciellin to the cornified envelope. Subcellular Location: Cytoplasm. Membrane. Note=May becomecross-linked to membrane proteins by transglutaminase. Tissue Specificity: Highly expressed in esophagus. It is alsoexpressed in keratinocytes, amniotic tissue, foreskin stratumspinosum and stratum granulosum, hair follicle and nail. Similarity: Contains 1 LIM zinc-binding domain. SWISS: O95171 Gene ID: 8796 Database links: UniProtKB/Swiss-Prot: O95171.2

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