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Product Name Anti-Host cell factor C2/PE Chinese Name PE标记的宿主cell factor2抗体 Alias C2 factor; HCF 2; HCF-2; HCF2; HCFC 2; HCFC2; HCFC2_HUMAN; Host cell factor 2. Research Area Cell biology Growth factors and hormones transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 87kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Host cell factor C2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008]
Subcellular Location:
Cytoplasm. Nucleus.
Tissue Specificity:
Highly expressed in testis. Detected at lower levels in spleen, thymus, prostate, ovary, small intestine and colon.
Similarity:
Contains 3 fibronectin type-III domains.
Contains 4 Kelch repeats.
Database links:Entrez Gene: 29915 Human
Entrez Gene: 67933 Mouse
Omim: 607926 Human
SwissProt: Q9Y5Z7 Human
SwissProt: Q9D968 Mouse
Unigene: 506558 Human
Unigene: 127405 Mouse
Unigene: 458243 Mouse
Unigene: 90662 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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